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The public's misperception of risk is one of the most important places to begin to educate the public and restore trust and confidence. The public believes largely that drugs should be free from side effects. This naive and misinformed perception crosses over into the public's view of clinical research. Whenever an adverse side effect is reported, the public tends to conclude—with the assistance of the media and overzealous politicians— that federal oversight is lax and that manufacturers have violated a sacred trust.

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