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Hydrosoluble medicated nail lacquers: in vitro drug permeation and corresponding antimycotic activity
British Journal of Dermatology, 11/06/09

Monti D et al. – Application of the CPX/sol nail lacquer allows rapid nail penetration of CPX, providing CPX levels sufficient to inhibit fungal growth for a prolonged period of time (30 h) after application of lacquer dose. CPX/sol nail lacquer appeared superior to the market reference Loceryl in terms of both vehicle (hydroxypropyl chitosan) and active ingredient (CPX) as witnessed by its higher efficacy on all nail pathogens.

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