Dermatology Medical News about Acne Vulgaris Propionibacterium acnes

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Choosing the best treatments for acne
The Clinical Advisor, 11/03/09

McMichael AJ et al. – Acne is a multifaceted skin disease that can have far–reaching consequences. The list of severe and devastating side effects may be short, but it is impressive. Early diagnosis and treatment are the mainstays of acne management and can prevent scarring, postinflammatory hyperpigmentation, and physical and psychosocial discomfort. The numerous drugs and technical modes available for the treatment of acne are a testament to the varied needs of acne patients. A balanced review of lesion type, patient requirements, and underlying expectations can make the difference in controlling acne vulgaris.

Acne severity correlates with increased anxiety, anger, and other negative psychological consequences.
Menstruation, pregnancy, and hyperandrogenic states can exacerbate acne.
Retinoids and retinoid–analogs prevent development of the microcomedo and comprise reasonable first–line agents.
A topical retinoid combined with an antibiotic (either topical or oral) yields greater and faster results than either used alone.

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Nicotinamide inhibits Propionibacterium acnes-induced IL-8 production in keratinocytes through the NF-kB and MAPK pathways
Journal of Dermatological Science, 10/06/09 Relevance Score: 88%

Interleukin-10 secretion from CD14+ peripheral blood mononuclear cells is downregulated in patients with acne vulgaris
British Journal of Dermatology, 10/13/09 Relevance Score: 82%

Propionibacterium acnes infection after shoulder arthroplasty: A diagnostic challenge
Journal of Shoulder and Elbow Surgery, 11/03/09 Relevance Score: 80%

Management of acne vulgaris: an evidence-based update
Clinical and Experimental Dermatology, 11/02/09 Relevance Score: 80%

Optical coherence tomography imaging of psoriasis vulgaris: correlation with histology and disease severity
Archives of Dermatological Research, 11/17/09 Relevance Score: 77%