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Efficacy of Dapsone in the Treatment of Pemphigus and Pemphigoid: Analysis of Current Data
American Journal of Clinical Dermatology, 10/20/09
Gurcan HM et al. – Dapsone is a promising and useful agent in patients with autoimmune mucocutaneous blistering diseases, especially in mucous membrane pemphigoid. It can be used as a corticosteroid–sparing agent. Therefore, its combined use with oral corticosteroids may be useful in pemphigus vulgaris and bullous pemphigoid. Adverse effects of dapsone are dose dependent and usually reversible. Hemolysis and concomitant anemia secondary to hemolysis are expected in most patients.
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