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Expression of tight-junction proteins in the inflamed and clinically uninvolved skin in patients with venous leg ulcers
Clinical and Experimental Dermatology, 10/12/09
Pavlovic MD et al. – Expression of claudin–1 was lost from the basal layer of the inflamed skin and skin under the hydrocolloid dressing. The skin on the lower legs affected by VLU may have altered expression of ZO–1 and claudin–1, similar to that seen in psoriatic plaques.
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