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Methotrexate is an antimetabolite that was first introduced as an anticancer drug. Due to its anti–inflammatory properties, it is now used – in much lower doses – for the treatment of joint, bowel and skin conditions. In dermatology, low–dose methotrexate is most commonly used to treat psoriasis that has not responded to topical treatments or phototherapy. It is also useful as a steroid–sparing agent in bullous pemphigoid, pemphigus, sarcoidosis, dermatomyositis and the vasculitides. Recently, it has been used in morphoea and in mycosis fungoides.

Today in Autoimmune/Bullous Dz...keeping you current

Pemphigus vegetans in a patient with colonic cancer
Indian Journal of Dermatology, Venereology and Leprology , 11/19/09

The immunocompromised district: a unifying concept for lymphoedematous, herpes-infected and otherwise damaged sites
Journal of the European Academy of Dermatology and Venereology, 11/16/09

Genome-Wide Association Study of Generalized Vitiligo in an Isolated European Founder Population Identifies SMOC2, in Close Proximity to IDDM8
Journal of Investigative Dermatology, 11/10/09

Today in Clinical Pharmacology...keeping you current

Ultrasound evaluation of clobetasol propionate 0.05% foam application in psoriatic and healthy skin: a pilot study
Dermatologic Therapy, 11/20/09

Cutaneous leishmaniasis treated with itraconazole
Dermatologic Therapy, 11/20/09

Topical treatment of melasma
Indian Journal of Dermatology, 11/20/09

Today in Derm Infectious Disease...keeping you current

Cutaneous leishmaniasis treated with itraconazole
Dermatologic Therapy, 11/20/09

The Antituberculosis Drug Pyrazinamide Affects the Course of Cutaneous Leishmaniasis In Vivo and Increases Activation of Macrophages and Dendritic Cells
Antimicrobial Agents and Chemotherapy, 11/20/09

Identification of B-Cell Epitopes on Virus-Like Particles of Cutaneous Alpha-Human Papillomaviruses
Journal of Virology, 11/20/09

Today in Dermatologic Oncology...keeping you current

Use of Oral N-Acetylcysteine for Protection of Melanocytic Nevi against UV-Induced Oxidative Stress: Towards a Novel Paradigm for Melanoma Chemoprevention
Clinical Cancer Research, 11/20/09

BRAF V600E mutation and the tumour suppressor IGFBP7 in atypical genital naevi
British Journal of Dermatology, 11/20/09

Eccrine spiradenoma with chondroid syringoma in Blaschkoid distribution
Indian Journal of Dermatology, Venereology and Leprology , 11/19/09

Today in Dermatopathology...keeping you current

Topical treatment of melasma
Indian Journal of Dermatology, 11/20/09

An overview of delayed pressure urticaria with special emphasis on pathogenesis and treatment
Dermatologic Therapy, 11/20/09

Iatrogenic Bullae Following Cupping Therapy
Journal of Alternative and Complementary Medicine, 11/20/09

Today in Photodermatology...keeping you current

Topical treatment of melasma
Indian Journal of Dermatology, 11/20/09

BRAF V600E mutation and the tumour suppressor IGFBP7 in atypical genital naevi
British Journal of Dermatology, 11/20/09

Low-fluence-rate photodynamic therapy to treat subfoveal choroidal neovascularization in pathological myopia. A study of efficacy and safety
Graefe's Archive for Clinical and Experimental Ophthalmology, 11/19/09


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