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Variability of prodromal signs and symptoms associated with hereditary angioedema attacks: A literature review
Allergy and Asthma Proceedings, 10/12/09
Kemp JG et al. – The review indicates that there is significant variability in the expression, manifestation, prevalence, timing, and predictive reliability of the prodromes that have been described. There is considerable variability of the prodromal manifestations that may occur before or during HAE attacks. The authors have not found any evidence that their sensitivity and specificity for accurately predicting such attacks has been studied.
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