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An organotypic culture system of Merkel cells using isolated epidermal sheets
British Journal of Dermatology, 10/13/09
Nagase K et al. – The data suggest, first, that direct contact between MCs and keratinocytes may be critical for retaining MCs in vitro; second, that nerve cell–affected maintenance of keratinocyte differentiation, but not NT–3 and NGF, may contribute to MC maintenance; and third, that MCs are not able to grow, at least in system.
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