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Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease
Journal of Experimental Medicine, 09/30/09
Kovalenko A et al. – The findings suggest that an enhanced response to endogenous activators of IRF3 in the epidermis, presumably generated in association with keratinocyte differentiation, contributes to the skin inflammatory process triggered by caspase–8 deficiency.
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