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Frigo L et al. – The authors data support the hypothesis that the physiological state of the cells affects the LLLT results, and that high–metabolic rate and short– cell–cycle 3T3 cells are not responsive to LLLT. In conclusion, LLLT with a dose of 3J reduced cell death significantly, but did not stimulate cell cycle. A LLLT dose of 21J had negative effects on the cells, as it increased cell death and inhibited cell proliferation.


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