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Depth profiling of Stratum corneum hydration in vivo: a comparison between conductance and confocal Raman spectroscopic measurements
Experimental Dermatology, 09/21/09

Boncheva M et al. – Conductometry of tape–stripped skin must be used in conjunction with a method that allows to estimate the barrier damage inflicted to SC during the tape–stripping procedure, for example, measurement of the trans–epidermal water loss. The methodology described here is simple, rapid and minimally invasive, and it employs commercially available instrumentation that is cheap, portable and easy to use. This approach is applicable to in vivo estimation of the SC hydration in studies in the areas of dermatology, skin care and transdermal drug delivery.

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