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Hear the Wnt Ror: how melanoma cells adjust to changes in Wnt
Pigment Cell & Melanoma Research, 09/11/09

Weeraratna AT et al. – Canonical Wnt signaling, represented by Wnts such as Wnt1 and Wnt3A, signals via beta–catenin to promote melanocyte differentiation and tumor development. Non–canonical Wnt signaling, specifically Wnt5A, regulates canonical pathways, and signals to induce melanoma metastasis.

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