Dermatology Medical News about C-Raf

Become a Member Today!
Register

Most Viewed Abstracts

1. Report Shows Shift in Starting Salaries for Physicians

2. 2008 Exclusive Survey—Earnings: Good news for primary care income

3. Medicare pay-for-reporting effort draws fire from frustrated doctors

4. Debunking Myths in the US Healthcare System

5. Doctors and the DEA Free full text

Your Article Summary

See Latest Articles

(Click the title below to leave the MDLinx Network and go to the Journal's Website)

C-Raf Is Associated with Disease Progression and Cell Proliferation in a Subset of Melanomas
Clinical Cancer Research, 09/15/09

Jilaveanu LB et al. – C–Raf siRNA knock–down results in decreased viability of YULAC (B–RafV600K) and YUROB (B–RafWT) melanoma cells, likely mediated by Bcl–2 inhibition rather than mitogen–activated protein kinase inhibition. Cotargeting C–Raf and parallel pathways might be an effective therapeutic approach for melanoma. C–Raf expression is up–regulated in a subset of melanomas but not in nevi, suggesting that it might be a valuable diagnostic marker and therapeutic target.

<< Previous
Familial disseminated plaque type porokeratosis with multiple...

Next >>
Accuracy of references cited in articles published in Indian...

A Short Hairpin DNA Analogous to miR-125b Inhibits C-Raf Expression, Proliferation, and Survival of Breast Cancer Cells
Molecular Cancer Research, 10/20/09 Relevance Score: 80%%