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Investigation of mutations in Erg11 gene of fluconazole resistant Candida albicans isolates from Turkish hospitals
Mycoses, 09/08/09

Yucesoy M et al. – Mutations such as K143R, G464S, G465S, V488I, S412T and R469K in the ERG11 gene were determined to be effective mechanisms in fluconazole R/SDD C. albicans isolates. Other mechanisms of resistance, such as overexpression of ERG11 and efflux pumps and mutations in the ERG3 gene should also be investigated.


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