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Autologous serum skin test: Methodology, interpretation and clinical applications
Indian Journal of Dermatology, Venereology and Leprology , 09/15/09

Vohra S et al. – The reported prevalence of ASST positivity in patients of chronic urticaria varies from 35 to 58% in various studies. Autologous serum skin test (ASST) positivity has been found to correlate well with the severity and duration of attacks of urticaria. However, it needs to be kept in mind that positive ASST does not specifically imply mast cell degranulation by autoimmune stimulation as a cause of the wheal response. It rather helps to define a subgroup of patients with chronic urticaria who are most likely to have endogenous cause and the results must be interpreted in the context of clinical relevance.

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