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See Latest ArticlesIntravenous Immunoglobulin-Induced, Non-Eczematous, Vesiculobullous Eruptions in Stevens-Johnson Syndrome
American Journal of Clinical Dermatology, 08/12/09
Lin WL et al. – The authors patient experienced an uncommon adverse effect, non–eczematous, vesiculobullous eruptions, after treatment with IVIG. These new lesions developed rapidly on the palms while most previous SJS bullous lesions subsided. A skin biopsy of these new lesions showed an intracorneal vesicle, without epidermal necrosis, with inflammatory cell infiltration. IVIG–induced, vesiculobullous eruptions are discussed, along with their possible pathogenesis. With the increasing use of IVIG for treatment of bullous dermatoses, recognition of this rare adverse effect is important for prompt differential diagnosis.
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