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Genetics of human iris colour and patterns
Pigment Cell & Melanoma Research, 08/04/09
Sturm RA et al. – A model is presented whereby this SNP, serving as a target site for the SWI/SNF family member HLTF, acts as part of a highly evolutionary conserved regulatory element required for OCA2 gene activation through chromatin remodelling. Major candidate genes possibly effecting iris patterns are also discussed, including MITF and PAX6.
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