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See Latest ArticlesOptimisation of Cosolvent Concentration for Topical Drug Delivery - II: Influence of Propylene Glycol on Ibuprofen Permeation
Skin Pharmacology and Applied Skin Physiology, 08/11/09
Watkinson RM et al. – An analysis of the partition and diffusion parameters for experiments conducted with skin confirmed that the influence of PG in the PG:water systems is primarily on the solubility and partitioning behaviour of ibuprofen. The ternary systems also appear to influence skin partition behaviour rather than diffusivity when compared with the permeation parameters of ibuprofen from saturated aqueous solutions.
Majella E. Lane, 08/11/09
| Propylene glycol is widely used as a co-solvent in the pharmaceutical and cosmetic industries. This study investigates the mechanisms underlying the ability of propylene glycol to effectively promote the permeation of materials into the skin. |
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