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Elder BL et al. – Scabies inhibited the IL–1 alpha and IL–1 beta–induced secretion of IL–6, while a combination of scabies and histamine or LTB4 reduced the TNF alpha–induced secretion of IL–6. Scabies extract inhibited secretion of IL–8. Histamine, PGD2, PGE2, LTB4, PAF, and IL–6 alone had no effect on this inhibition, but the scabies–induced inhibition of IL–8 secretion was reduced in a dose–dependent fashion in the presence of IL–1 alpha and IL–1 beta.

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