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Grimes PE et al. – Hydroquinone remains the gold standard of topical agents. Other efficacious agents include kojic acid, azelaic acid, mequinol, and retinoids. Cosmeceutical agents include licorice, arbutin, soy, N–acetyl glucosamine, and niacinamide. Resurfacing procedures that have been used to treat melasma and PIH include chemical peels, microdermabrasion, lasers, and intense pulsed light. These procedures are best used in combination with topical bleaching agents. Maximal results are best achieved with repetitive, superficial, resurfacing modalities. In addition, ultraviolet protective measures such as broad–spectrum sunscreens are fundamental to the successful management of these conditions.

Today in Clinical Pharmacology...keeping you current

Pulsed High-Dose Corticosteroids Combined With Low-Dose Methotrexate Treatment in Patients With Refractory Generalized Extragenital Lichen Sclerosus
Archives of Dermatology, 11/25/09

Topical Calcipotriol for Preventive Treatment of Hypertrophic Scars
Archives of Dermatology, 11/25/09

Failure of omalizumab in cholinergic urticaria
Clinical and Experimental Dermatology, 11/25/09

Today in Cosmetic Derm/Acne...keeping you current

Leucoderma after use of a skin-lightening cream containing kojic dipalmitate, liquorice root extract and Mitracarpus scaber extract
Clinical and Experimental Dermatology, 11/25/09

Aquagenic Wrinkling of the Palms in Cystic Fibrosis
Archives of Dermatology, 11/25/09

Delayed Inflammatory Reaction to Bio-Alcamid Polyacrylamide Gel Used for Soft-Tissue Augmentation
Archives of Dermatology, 11/25/09

Today in Laser Surgery...keeping you current

In vivo comparison of near infrared lasers for skin welding
Lasers in Medical Science, 11/24/09

Effect of Low-Level Laser Therapy on Malondialdehyde Concentration in Random Cutaneous Flap Viability
Photomedicine and Laser Surgery, 11/24/09

Multiphoton Laser Scanning Microscopy-A Novel Diagnostic Method for Superficial Skin Cancers
Seminars in Cutaneous Medicine and Surgery, 11/18/09

Today in Photodermatology...keeping you current

Fluorescence remission spectroscopy of psoriatic lesions and the effect of topical anthralin therapy
Journal of the European Academy of Dermatology and Venereology, 11/24/09

Recurrence pattern in squamous cell carcinoma of skin of lower extremities and abdominal wall (Kangri cancer) in Kashmir valley of Indian subcontinent: Impact of various treatment modalities
Indian Journal of Dermatology, 11/23/09

Topical treatment of melasma
Indian Journal of Dermatology, 11/20/09


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