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Could local delivery of bisphosphonates be a new therapeutic choice for hemangiomas
Medical Hypotheses, 07/28/09
Yu H et al. – Local deliver of bisphosphonates by fine calcium phosphate particles may be a potential treatment of hemangiomas. By employing proper calcium phosphate particles, bioactive bisphosphonates will be gradually released and exert their anti–angiogenesis effect, destructing rapid proliferation of epithelial cells and promoting the involution of hemangiomas without systematic adverse side effects.
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