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Greener M – The risk of adverse events prompted the search for better–tolerated alternatives, including topical preparations. Despite some initial scepticism, a growing body of clinical and pharmacological evidence suggests that topical NSAIDs offer an effective and well–tolerated treatment for several conditions that produce chronic or acute pain. This article briefly describes the history of NSAIDs and how they work, before focusing on the use of topical NSAIDs as a therapeutic option.

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