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Dermal Hyaluronan Is Rapidly Reduced by Topical Treatment with Glucocorticoids
Journal of Investigative Dermatology, 07/23/09
Gebhardt C et al. – The data show that the levels of skin HA rapidly decrease after short–term GC treatment due to a reduction in HA synthesis, while HA degradation is not changed. This may reflect an initiation of skin atrophy in response to topically applied GCs.
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