Your Messages Inbox
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. 2008 Exclusive Survey—Earnings: Good news for primary care income 3. Medicare pay-for-reporting effort draws fire from frustrated doctors 4. Debunking Myths in the US Healthcare System 5. Doctors and the DEA Free full text
Top Ten Searches
rosacea eczema alopecia ceramide keratosis pityriasis basal cell melanoma keratosis purpuraYour Article Summary
See Latest ArticlesDexamethasone and hypoxia upregulate CXCR4 expression in myeloma cells
Leukemia and Lymphoma, 07/02/09
Kim SW et al. - Incubation of cells under hypoxic conditions (1% O2) also induced upregulation of CXCR4 in the cytoplasm and on the cell surface and enhanced chemotaxis in response to stromal cell-derived factor-1 (SDF-1). Cell surface CXCR4 expression was more prominent in annexin V-positive apoptotic cells. Given the roles of the SDF-1/CXCR4 axis in the development and progression of myeloma, CXCR4-downregulating agents may enhance the antitumor effects of dexamethasone.
Related Articles
Multiple myeloma and cutaneous anaplastic large T-cell lymphoma in the same patient: Is there a causal relation
Journal of Cutaneous Pathology, 11/09/09
Relevance Score: 67%
Initial cytoreductive treatment with thalidomide plus bolus vincristine/doxorubicin and reduced dexamethasone followed by autologous stem cell transplantation for multiple myeloma
Investigational New Drugs, 10/23/09
Relevance Score: 67%
Retrospective comparison of mobilization methods for autologous stem cell transplantation in multiple myeloma
American Journal of Hematology, 11/10/09
Relevance Score: 66%
Primary plasma cell leukemia
Cancer, 11/04/09
Relevance Score: 66%
Functional Interaction of Plasmacytoid Dendritic Cells with Multiple Myeloma Cells: A Therapeutic Target
Cancer Cell, 10/12/09
Relevance Score: 66%
Today in Clinical Pharmacology...keeping you current
Receive free subspecialty "5-minute updates" via email
Low-dose methotrexate treatment for moderate-to-severe atopic dermatitis in adults
Journal of the European Academy of Dermatology and Venereology, 12/17/09
Multiple epidermal cysts occcurring in a tattoo
Singapore Medical Journal, 12/17/09
Efficacy and safety of linezolid in methicillin-resistant Staphylococcus aureus complicated skin and soft tissue infection: a meta-analysis
Current Medical Research and Opinion, 12/17/09
Today in Dermatologic Oncology...keeping you current
Receive free subspecialty "5-minute updates" via email
Pathology Review of Thin Melanoma and Melanoma in Situ in a Multidisciplinary Melanoma Clinic: Impact on Treatment Decisions
Journal of Clinical Oncology, 12/18/09
Syringoma of the face treated with fractional photothermolysis
Journal of Cosmetic and Laser Therapy, 12/18/09
Somatostatin receptor scintigraphy in primary cutaneous T- and B-cell lymphomas
Journal of the European Academy of Dermatology and Venereology, 12/18/09
Sponsor
Article Search
Sponsor
Sponsor