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Impact of Scratching on Itch and Sympathetic Reflexes Induced by Cowhage (Mucuna pruriens) and Histamine
Acta Dermato-Venereologica, 06/24/09

Kosteletzky F et al. - Cowhage and histamine, both applied via spicules, were used to induce itch. The quality and intensity of the sensations, axon reflex flare, sympathetic skin vasoconstrictions and the interference of scratching with itch processing were studied. The findings support the notion that both agents activate different pathways. The differences in sympathetic reflex induction and in the modulation by scratching indicate differential central nervous processing.

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Itch and pain
Neuroscience & Biobehavioral Reviews, 11/05/09 Relevance Score: 95%%

Effect of a novel kappa-receptor agonist, nalfurafine hydrochloride, on severe itch in 337 haemodialysis patients: a Phase III, randomized, double-blind, placebo-controlled study
Nephrology Dialysis Transplantation, 11/24/09 Relevance Score: 83%%

Time to onset and duration of action of the antihistamine bepotastine besilate ophthalmic solutions 1.0% and 1.5% in allergic conjunctivitis: A phase III, single-center, prospective, randomized, double-masked, placebo-controlled, conjunctival allergen challenge assessment in adults and children
Clinical Therapeutics, 10/29/09 Relevance Score: 80%%

Botox Sponge Replaces Needles for Rhinitis Patients
Ivanhoe, 10/19/09 Relevance Score: 80%%

Uraemic pruritus: starting from scratch to relieve itch
Drugs & Therapy Perspectives, 10/16/09 Relevance Score: 80%%