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Aldo-keto reductase 1C subfamily genes in skin are UV-inducible: possible role in keratinocytes survival
Experimental Dermatology, 06/18/09
Marin YE et al. - Based on the combined evidence of the presence of an apoptotic marker in the UVB-exposed keratinocytes with increased AKR1Cs expression and reduced cell viability in down-regulated AKR1Cs, the authors suggest that AKR1C subfamily genes are stress-inducible and might function as survival factors in keratinocytes.
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