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Atypical paraneoplastic pemphigus secondary to endometrial carcinoma with no mucosal involvement
Clinical and Experimental Dermatology, 06/16/09
Kennedy NA et al. - The authors report a case of a 78-year-old woman presenting with an atypical form of PNP associated with a recurrence of endometrial cancer. There was no involvement of the mucous membranes. Although the macroscopic and histological appearances were typical for IgA pemphigus or Sneddon-Wilkinson disease, direct immunofluorescence was positive for intercellular IgG and C3 staining. Circulating antibodies were detected to periplakin and envoplakin, but not to desmogleins 1 or 3.
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