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See Latest ArticlesThe pathogenesis of psoriatic arthritis and associated nail disease: not autoimmune after all
Current Opinion in Rheumatology, 06/11/09
McGonagle D et al. - Recent microanatomical studies confirm that normal tendon and ligament insertion points to bone (entheses), the key territory for the inflammatory reaction associated with PsA, being subject to microdamage that strongly points to a role for microtrauma in the joints, which is reminiscent of Koebner responses in the skin. Furthermore, the nail is functionally integrated with entheses associated with the distal phalanx that provides anchorage to the skin and joint.
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Site of psoriasis (scalp or intergluteal/perianal), >=3 affected sites, and nail dystrophy predicted psoriatic arthritis in incident psoriasis
Evidence-Based Medicine, 12/07/09
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