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Federman DG et al. - Psoriasis is a prevalent immune disease most notably recognized for its involvement of the skin and joints and for its impact on patient quality of life. More recently, it has been shown that not only do patients with psoriasis have a higher prevalence of cardiovascular risk factors such as hypertension, diabetes mellitus, obesity, smoking, and dyslipidemia, but they also appear to have an increased risk of myocardial infarction independent of these factors. Patients with severe forms of psoriasis also have been found to have increased mortality rates compared to those without psoriasis.

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