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Recovery fluorescence after 5-ALA-induced PpIX-photodynamic therapy
Medical Laser Application, 05/21/09
Philipp CM et al. - The finding of a recovery-fluorescence suggests excess amount of 5-ALA in the lesions, deeper penetration of 5-ALA with extended incubation times, local persistence of viable cells being able to produce PpIX after first irradiation, a need for an individualized light and drug dosimetry including prolonged incubation times, repeated irradiation and fluorescence control during topically ALA-induced PpIX-PDT.
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