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Yu HS et al. - The authors have demonstrated that the He-Ne laser imparts a growth stimulatory effect on functional melanocytes via mitochondri-related pathways and proposed that other minor pathways including DNA damage may also be inflicted by laser treatment on irradiated cells. More importantly, the authors have completed the repigmentation scheme of vitiligo brought about by He–Ne laser light in vitro and provided a solid theoretical basis regarding how the He–Ne laser induces recovery of vitiligo in vivo.

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