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See Latest ArticlesAberrant Notch signaling: A potential pathomechanism of vitiligo
Medical Hypotheses, 03/27/09
Diao JS et al. - Vitiligo is characterized by a localized and progressive loss of melanocytes which are pigment cells responsible for the pigmentation of human. Activation of Notch signaling occurs during the formation of melanocytic tumors and inactivation of Notch signaling causes a dramatic elimination of melanocytes precursors.
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