Dermatology Medical News about Discoid Lupus Erythematosus

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Early diagnosis and treatment of discoid lupus erythematosus
Journal of the American Board of Family Medicine, 03/11/09

Panjwani S et al – Article discusses the importance of early recognition, and treatment of discoid lupus erythematosus (DLE), a chronic dermatological disease that can lead to scarring, hair loss, and hyperpigmentation changes in skin if it is not treated early and promptly. The diagnosis is usually made by clinical examination, histopathology of an inflammatory interface dermatosis. Because lesions are induced or exacerbated by UV exposure, photoprotective measures are important. Potent topical steroids and antimalarials are the mainstay of treatment; retinoids, thalidomide, and topical tacrolimus, immunosuppressives like azathioprine, cyclosporine, mycophenolate mofetil, and methotrexate offer alternatives.

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