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Intermittent Pressure Decreases Human Keratinocyte Proliferation in vitro
Skin Pharmacology and Applied Skin Physiology, 09/17/07
Nascaa, M.R., et al. - Conclusion: These data indicate that keratinocytes undergoing intermittent pressure changes exhibit decreased proliferation rates compared to controls. Furthermore, an increased frequency rate seems to have a greater effect on proliferation than low-frequency rate pressure changes, suggesting that the stress caused by frequently changed pressure may play a greater role in reducing keratinocyte proliferation than the actual magnitude of load applied to the cells
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