Eruptive papules during efalizumab (anti-CD11a) therapy of psoriasis vulgaris: a case series Lowes, M.A., et al. - Newer biological therapies for moderate-to-severe psoriasis are being used more frequently, but unexpected effects may occur...Conclusion: We hypothesize that these papules may represent a unique type of "mechanistic" inflammatory reaction, seen only in the context of drug-induced CD11a blockade, and not during the natural disease process [more...]