Short telomeres in an oral precancerous lesion: Q-FISH analysis of leukoplakia
Journal of Oral Pathology & Medicine, 05/07/2012
Aida J et al. – Ortho–keratotic dysplasia appears to be frequently associated with carcinoma, chromosomal instability, and excessively shortened telomeres, not only in the lesion itself but also in the surrounding background. Therefore, when this type of leukoplakia is recognized in the oral region, strict follow–up for oral squamous cell carcinoma is necessary, focusing not only on the areas of leukoplakia, but also the surrounding background.