Platelet activation correlates with disease severity in urticarial
As reported in Platelets, the mean platelet volume, platelet distribution width, platelet aggregation, and soluble P-selectin levels were elevated in patients with chronic urticaria (n=45) compared to healthy controls.
Risk factors for mortality in patients with pressure ulcers
As reported in the International Wound Journal, 90- and 180-day mortality amongst hospitalized patients with pressure ulcers was associated with diabetes, chronic renal failure, congestive heart failure, and metastatic cancer. Ninety-day, but not 180-day mortality, was associated with myocardial infarction, cerebrovascular disease, liver disease, and HIV/AIDS. The only laboratory parameter associated with mortality rates was albumin.
DCL1 is a tumor suppressor in melanoma patients
As reported in Modern Pathology, down-regulation of cytoplasmic and nuclear DLC1 is associated with poor overall survival and disease-specific 5-y survival in all melanoma patients. Combined down-regulation of cytoplasmic and nuclear DCL1 was associated with the worse survival for patients with metastatic melanoma.