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Dermatology - Basic Science/Genetics News & Articles

MDLinx.com consistently provides the most current Dermatology medical news articles and clinical articles daily, from over 2,000 peer-reviewed journals. Topics covered range from: Cosmetic Dermatology, Clinical Pharmacology, Dermatologic Surgery and Dermatopathology, just to name few. The MDLinx medical editors meticulously categorize and summarize clinical articles daily within 24 hours of publication to keep you abreast of with the most relevant medical news.

On this page you may also find bonus content specifically chosen by our Physician Senior Editor D. Scott Cunningham, MD, PhD, along with clinical pearls from the Smartest Doc, our daily quiz competition and Dermatology Physician Review.

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Your Unread Messages in Dermatology

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Articles

Latest (3) Full Text Articles (86) Focus on Dermatopathology
Ranked, sorted, and summarized by MDLinx editors from the latest literature
Topics:

761 Filaggrin polymorphism P478S, IgE level, and atopic phenotypes British Journal of Dermatology, January 19, 2011

762 Expression of the soluble vascular endothelial growth factor receptor-1 in cutaneous melanoma: role in tumour progression British Journal of Dermatology, January 17, 2011

763 Collagen triple helix repeat containing 1 inhibits TGF-beta1-induced collagen type I expression in keloid British Journal of Dermatology, January 17, 2011

764 Examination of AKAP12 promoter methylation in skin cancer using methylation-sensitive high-resolution melting analysis Clinical and Experimental Dermatology, January 17, 2011

765 Peoniflorin suppresses tumor necrosis factor-alpha induced chemokine production in human dermal microvascular endothelial cells by blocking nuclear factor-kappa B and ERK pathway Archives of Dermatological Research, January 14, 2011

766 THAP5 is a DNA-binding transcriptional repressor that is regulated in melanoma cells during DNA damage-induced cell death Biochemical and Biophysical Research Communications, January 14, 2011

767 Evidence for a Pathophysiological Role of Keratinocyte-Derived Type III Interferon (IFNlambda) in Cutaneous Lupus Erythematosus Full Text Journal of Investigative Dermatology, January 13, 2011

768 Steroid synthesis by primary human keratinocytes; implications for skin disease Biochemical and Biophysical Research Communications, January 13, 2011

769 Absence of BRAF and HRAS mutations in eruptive Spitz nevi British Journal of Dermatology, January 12, 2011

770 Immunophenotyping of inflammatory cells in subacute prurigo Journal of the European Academy of Dermatology and Venereology, January 12, 2011

771 Investigation of the Molecular Structure of the Human Stratum Corneum Ceramides [NP] and [EOS] by Mass Spectrometry Skin Pharmacology and Physiology, January 12, 2011

772 Expression and Function of the Natural Cytotoxicity Receptor NKp46 on Circulating Malignant CD4 + T Lymphocytes of Sezary Syndrome Patients Journal of Investigative Dermatology, January 11, 2011

773 Evidence for the absence of mutations at GJB3, GJB4 and LOR in progressive symmetrical erythrokeratodermia Clinical and Experimental Dermatology, January 11, 2011

774 A Japanese-specific recurrent mutation and a novel splice site mutation in the LAMC2 gene identified in two Japanese families with Herlitz junctional epidermolysis bullosa Clinical and Experimental Dermatology, January 11, 2011

775 Development of atopic dermatitis-like skin disease from the chronic loss of epidermal caspase-8 Full Text Proceedings of the National Academy of Sciences of the United States of America, January 10, 2011

776 The regulatory mechanism of melanogenesis by FTY720, a sphingolipid analogue Experimental Dermatology, January 10, 2011

777 Reduction of skin-homing cytotoxic T cells (CD8+ - CLA+) in patients with vitiligo Photodermatology, Photoimmunology and Photomedicine, January 10, 2011

778 Impaired IFN- alpha secretion by plasmacytoid dendritic cells induced by TLR9 activation in chronic idiopathic urticaria British Journal of Dermatology, January 7, 2011

779 A novel homozygous splice site mutation in COL7A1 in a Chinese patient with severe recessive dystrophic epidermolysis bullosa and squamous cell carcinoma International Journal of Dermatology, January 7, 2011

780 New homozygous SPINK5 mutation, p.Gln333X, in a Turkish pedigree with Netherton syndrome Clinical and Experimental Dermatology, January 7, 2011

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Clinical Pearls in Dermatology

Highlights in Dermatology

Factors affecting treatment response in alopecia areata

As published in the Journal of European Academy of Dermatology & Venereology, measureable autoantibodies were associated with an increased extent of alopecia areata (AA). Ophiasic hair loss and nail dystrophy were associated with atopic AA, which in turn was associated with an increased risk of relapse.

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Chondroitinase ABC reduces keloids

As published in the Journal of Dermatology, injection of chondroitinase ABC into keloid grafted on to nude mice resulted in a significant reduction in keloid formation and elastic fiber formation.

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LL-37 is a biomarker of eczema severity in children

LL-37 corresponds to amino acids 134-170 in human cathelicidin, which is involved in innate immunity against cutaneous infections. Researchers at the Chinese University of Hong Kong conducted a study involving 144 children with eczema and 36 healthy children. The LL-37 levels were shown to be associated with the atopic dermatitis scores and the severity of eczema. The authors suggest that LL-37 is a biomarker of eczema severity in children and that innate immunity underlies the pathogenesis of eczema.

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Most Popular Dermatology Articles

Last month's top read Top Articles of 2012

1 Merkel cell carcinoma concurrent with Bowens disease: Two cases, one with an unusual immunophenotype Journal of Cutaneous Pathology, May 15, 2013

2 Digital Necrosis from Dandelion Tea British Journal of Dermatology, March 1, 2013

3 Comparison between fibroblasts and mesenchymal stem cells derived from dermal and adipose tissue International Journal of Cosmetic Science, May 14, 2013

4 Pruritus to anticancer agents targeting the EGFR, BRAF, and CTLA-4 Dermatologic Therapy, April 24, 2013    Review Article

5 Molecular Signatures in Skin Associated with Clinical Improvement during Mycophenolate Treatment in Systemic Sclerosis Journal of Investigative Dermatology, May 21, 2013    Review Article

6 Inhibition of Melanoma Growth by Small Molecules That Promote the Mitochondrial Localization of ATF2 Clinical Cancer Research, May 2, 2013    Review Article

7 Overview of skin diseases linked to connexin gene mutations International Journal of Dermatology, May 24, 2013    Review Article

8 Emerging role for the killer-cell immunoglobulin-like receptors genotype, in the susceptibility of skin diseases Journal of Dermatological Science, May 6, 2013

9 ADAR1 p150 isoform is involved in the pathogenesis of dyschromatosis symmetrica hereditaria British Journal of Dermatology, May 10, 2013

10 BRAF mutational epidemiology in dysplastic nevi: Does different solar UV radiation exposure matter Journal of the European Academy of Dermatology and Venereology, March 29, 2013

11 Generalized and Naevoid Epidermolytic Ichthyosis in Denmark: Clinical and Mutational Findings Acta Dermato-Venereologica, May 17, 2013    Review Article

12 Hairless down-regulates expression of msx2 and its related target genes in hair follicles Journal of Dermatological Science, May 29, 2013    Review Article

13 Mast cells play a key role in host defense against herpes simplex virus infection through TNF-α and IL-6 production Journal of Investigative Dermatology, May 15, 2013

14 Environmental study of azole-resistant aspergillus fumigatus with tr34/l98h mutations in the cyp51a gene in Iran Mycoses, May 22, 2013    Review Article

15 Unusual Clinical Manifestations in a Case of Alagille Syndrome Pediatric Dermatology, April 8, 2013

16 Autophagy Has a Significant Role in Determining Skin Color by Regulating Melanosome Degradation in Keratinocytes Journal of Investigative Dermatology, May 16, 2013    Review Article

17 Streptococcus sanguinis and the sera of patients with Behçets disease stimulate membrane expression of α-enolase in human dermal microvascular endothelial cells Archives of Dermatological Research, April 2, 2013

18 Skin tags: A link between lesional mast cell count/tryptase expression and obesity and dyslipidemia Indian Journal of Dermatology, May 7, 2013    Free full text    Review Article

19 Senescent Fibroblasts Enhance Early Skin Carcinogenic Events via a Paracrine MMP-PAR-1 Axis PLOS ONE, May 17, 2013    Review Article

20 Psoriasis and streptococci: the natural selection of psoriasis revisited British Journal of Dermatology, March 23, 2009

Indexed Journals in Dermatology: American Journal of Clinical Dermatology, Contact Dermatitis, Dermatologic Surgerymore

Other Topics in Dermatology

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