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Dermatology - Basic Science/Genetics News & Articles
MDLinx.com consistently provides the most current Dermatology medical news articles and clinical articles daily, from over 2,000 peer-reviewed journals. Topics covered range from: Cosmetic Dermatology, Clinical Pharmacology, Dermatologic Surgery and Dermatopathology, just to name few. The MDLinx medical editors meticulously categorize and summarize clinical articles daily within 24 hours of publication to keep you abreast of with the most relevant medical news.
On this page you may also find bonus content specifically chosen by our Physician Senior Editor D. Scott Cunningham, MD, PhD, along with clinical pearls from the Smartest Doc, our daily quiz competition and Dermatology Physician Review.
Sign up today to learn more about upcoming Dermatology conferences, Continuing Medical Education (CME) opportunities, receive daily newsletters and more.
Your Unread Messages in Dermatology
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Altered anti-microbial peptides associated with atopic dermatitis severity -
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Articles
Latest (3) Full Text Articles (86) Focus on Autoimmune Diseases281 Liver X Receptor Activation Inhibits Melanogenesis through the Acceleration of ERK-Mediated MITF Degradation Journal of Investigative Dermatology, December 19, 2012
282 Reduced Il17a Expression Distinguishes a Ly6cloMHCIIhi Macrophage Population Promoting Wound Healing Journal of Investigative Dermatology, December 19, 2012
283 Differentiation of Human Embryonic Stem Cells into Clinically Amenable Keratinocytes in an Autogenic Environment Journal of Investigative Dermatology, December 18, 2012
284 Report of a novel OCA2 gene mutation and an investigation of OCA2 variants on melanoma risk in a familial melanoma pedigree Journal of Dermatological Science, December 17, 2012
285 Increased Incidence of Cutaneous Nontuberculous Mycobacterial Infection, 1980 to 2009: A Population-Based Study Mayo Clinic Proceedings, December 14, 2012
286 Foxp3+ Regulatory T Cells Are Increased in the Early Stages of Halo Nevi: Clinicopathological Features of 30 Halo Nevi Dermatology, December 14, 2012
287 Azelaic acid reduced senescence-like phenotype in photo-irradiated human dermal fibroblasts: possible implication of PPAR Experimental Dermatology, December 12, 2012
288 Oligosaccharides of hyaluronic acid increased epidermal cell stemness by modulation of integrin expression Journal of Cosmetic Dermatology, December 10, 2012
289 The Basic Science of Hair Biology: What Are the Causal Mechanisms for the Disordered Hair Follicle Dermatologic Clinics, December 6, 2012
290 Galectin-7 and actin are components of amyloid deposit of localized cutaneous amyloidosis Experimental Dermatology, November 29, 2012
291 Prevalence of the E318K MITF germline mutation in Italian melanoma patients: associations with histological subtypes and family cancer history Pigment Cell & Melanoma Research, November 26, 2012
292 Gene Profiling of Narrowband UVB–Induced Skin Injury Defines Cellular and Molecular Innate Immune Responses Journal of Investigative Dermatology, November 20, 2012
293 miR-137 Inhibits the Invasion of Melanoma Cells through Downregulation of Multiple Oncogenic Target Genes Journal of Investigative Dermatology, November 16, 2012
294 Freeze drying as a preserving preparation technique for in vitro testing of human skin Experimental Dermatology, November 13, 2012
295 Transcription Factor Ctip2 Controls Epidermal Lipid Metabolism and Regulates Expression of Genes Involved in Sphingolipid Biosynthesis during Skin Development Journal of Investigative Dermatology, November 12, 2012
296 Selected variants of the melanocortin 4 receptor gene (MC4R) do not confer susceptibility to female pattern hair loss Archives of Dermatological Research, November 12, 2012
297 Association between -308 G/A polymorphism in TNF- α gene and lichen planus: A meta-analysis Journal of Dermatological Science, November 6, 2012 Evidence Based Medicine
298 Deletion of the Sox21 gene drastically affects hair lipids Experimental Dermatology, November 5, 2012
299 A novel mutation of CYLD in a Chinese family with multiple familial trichoepithelioma Journal of the European Academy of Dermatology and Venereology, November 2, 2012
300 Impact Of Toll-Like Receptor-4 And Tumor Necrosis Factor Genes Polymorphisms In Patients With Hidradenitis Suppurativa British Journal of Dermatology, October 30, 2012
Clinical Pearls in Dermatology
- Psoriatic skin lesions are characterized by an inflammatory infiltrate consisting of both CD4(+) and CD8(+) T lymphocytes.
- The resultant toxicity of cytotoxic agents commonly affects the bone marrow, skin and intestinal epithelium
- Patients with severe acne can see better results after 16 weeks of therapy on a lower-dose isotretinoin regimen of 1 mg/kg/day
Highlights in Dermatology
Factors affecting treatment response in alopecia areata
As published in the Journal of European Academy of Dermatology & Venereology, measureable autoantibodies were associated with an increased extent of alopecia areata (AA). Ophiasic hair loss and nail dystrophy were associated with atopic AA, which in turn was associated with an increased risk of relapse.
Read the article summaryChondroitinase ABC reduces keloids
As published in the Journal of Dermatology, injection of chondroitinase ABC into keloid grafted on to nude mice resulted in a significant reduction in keloid formation and elastic fiber formation.
Read the article summaryLL-37 is a biomarker of eczema severity in children
LL-37 corresponds to amino acids 134-170 in human cathelicidin, which is involved in innate immunity against cutaneous infections. Researchers at the Chinese University of Hong Kong conducted a study involving 144 children with eczema and 36 healthy children. The LL-37 levels were shown to be associated with the atopic dermatitis scores and the severity of eczema. The authors suggest that LL-37 is a biomarker of eczema severity in children and that innate immunity underlies the pathogenesis of eczema.
Read the article summaryMost Popular Dermatology Articles
Last month's top read Top Articles of 2012Indexed Journals in Dermatology: American Journal of Clinical Dermatology, Contact Dermatitis, Dermatologic Surgery more
Other Topics in Dermatology
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