Down-regulation of IGF-1 involved in male pattern baldness
As reported in Experimental Dermatology, secretion of IGF-1, IGFBP-2, and IGFBP-4 is decreased in the dermal papillae of balding hair follicles compared to non-balding hair follicles.
sCD40L suggests sub-clinical atherosclerosis in psoriasis
As reported in the International Journal of Dermatology, sCD40L levels are elevated and brachial artery flow-mediated dilation is decreased in patients with chronic plaque-type psoriasis (n=56) without known cardiovascular disease compared to healthy controls.
Psoriasis associated with NAFLD in elderly
As reported in the Journal of the American Academy for Dermatology, non-alcoholic fatty liver disease (NAFLD) is more common in patients > 55 years of age with psoriasis. The prevalence of NAFLD in patients with and without psoriasis was 46.2% and 33.3% (OR = 1.7), respectively.