DCL1 is a tumor suppressor in melanoma patients
As reported in Modern Pathology, down-regulation of cytoplasmic and nuclear DLC1 is associated with poor overall survival and disease-specific 5-y survival in all melanoma patients. Combined down-regulation of cytoplasmic and nuclear DCL1 was associated with the worse survival for patients with metastatic melanoma.
Risk factors for mortality in patients with pressure ulcers
As reported in the International Wound Journal, 90- and 180-day mortality amongst hospitalized patients with pressure ulcers was associated with diabetes, chronic renal failure, congestive heart failure, and metastatic cancer. Ninety-day, but not 180-day mortality, was associated with myocardial infarction, cerebrovascular disease, liver disease, and HIV/AIDS. The only laboratory parameter associated with mortality rates was albumin.
Pantothenic acid effective for acne
As reported in Dermatology and Therapy, a pantothenic acid-based dietary supplement for 12 weeks reduced the total lesion count, number of inflammatory lesions, and DLQI in patients with mild-to-moderate acne (n=41) compared to placebo.