Obesity and risk of incident psoriatic arthritis in US women
Annals of Rheumatic Diseases,

Li W et al. – This study provides further evidence linking obesity with the risk of incident psoriatic arthritis (PsA) among US women.

  • 89 049 participants were included from the Nurses Health Study II over a 14–year period (1991–2005).
  • Information on body mass index (BMI), weight change and measures of central obesity (waist circumference, hip circumference and waist–hip ratio) was collected during the follow–up.
  • The incidence of clinician–diagnosed PsA was ascertained and confirmed by supplementary questionnaires.

  • 146 incident PsA cases were identified during 1 231 693 person–years of follow–up.
  • Among all participants, BMI was monotonically associated with an increased risk of incident PsA.
  • Compared with BMI less than 25.0, the RR was 1.83 for BMI 25.0–29.9 (95% CI 1.15 to 2.89), 3.12 for BMI 30.0–34.9 (95% CI 1.90 to 5.11) and 6.46 for BMI over 35.0 (95% CI 4.11 to 10.16).
  • There was a graded positive association between weight change from age 18 years, measures of central obesity and risk of PsA (p for trend <0.001).
  • The analysis among participants developing psoriasis during follow–up revealed a similar association (p for trend <0.01), indicating an increased risk of PsA associated with obesity among patients with psoriasis.

Please login or register to follow this author.
► Click here to access PubMed, Publisher and related articles...
<< Previous Article | Next Article >>

Your Unread Messages in Dermatology

See All >> Messages include industry-sponsored communications and special communications from MDLinx

Most Popular Dermatology Articles

1 Vitamin D and melanoma and non-melanoma skin cancer risk and prognosis: A comprehensive review and meta-analysis European Journal of Cancer, August 7, 2014    Review Article

2 Anti-aging and filling efficacy of six types hyaluronic acid based dermo-cosmetic treatment: Double blind, randomized clinical trial of efficacy and safety Journal of Cosmetic Dermatology, November 20, 2014    Clinical Article

3 2014 European guideline on the management of syphilis Journal of the European Academy of Dermatology and Venereology, November 12, 2014    Clinical Guideline

4 Chronic urticaria: new management options Full Text World Allergy Organization Journal, November 19, 2014    Free full text    Review Article

5 Evidence based topical treatments for tinea cruris and tinea corporis: A summary of a Cochrane systematic review British Journal of Dermatology, October 24, 2014    Evidence Based Medicine    Review Article

6 An open label prospective randomized trial to compare the efficacy of coal tar-salicylic acid ointment versus calcipotriol/betamethasone dipropionate ointment in the treatment of limited chronic plaque psoriasis Full Text Indian Journal of Dermatology, November 19, 2014    Free full text    Clinical Article

7 Psoriasis is not an autoimmune disease? Experimental Dermatology, November 12, 2014    Clinical Article

8 Guidelines of care for the management of atopic dermatitis Journal of the American Academy of Dermatology, November 7, 2014    Clinical Guideline

9 Skin-whitening and skin-condition-improving effects of topical oxidized glutathione: A double-blind and placebo-controlled clinical trial in healthy women Full Text Clinical, Cosmetic and Investigational Dermatology, November 3, 2014    Free full text    Clinical Article

10 Sun protection in a pill: The photoprotective properties of Polypodium leucotomos extract International Journal of Dermatology, July 28, 2014    Review Article

11 Treatment of acne with tea tree oil (melaleuca) products: A review of efficacy, tolerability and potential modes of action International Journal of Antimicrobial Agents, November 18, 2014    Review Article

12 Margins in skin excision biopsies: Principles and guidelines Full Text Indian Journal of Dermatology, November 14, 2014    Free full text    Clinical Guideline

13 Preliminary open-label clinical evaluation of the soothing and reepithelialization properties of a novel topical formulation for rosacea Full Text Clinical, Cosmetic and Investigational Dermatology, November 10, 2014    Free full text    Clinical Article

14 Use of biologic agents in combination with other therapies for the treatment of psoriasis American Journal of Clinical Dermatology, November 26, 2014    Review Article

15 Photochemotherapy (PUVA) in psoriasis and vitiligo Full Text Indian Journal of Dermatology, Venereology and Leprology , November 21, 2014    Free full text    Clinical Guideline

16 Randomized trial of vitamin D supplementation for winter-related atopic dermatitis in children The Journal of Allergy and Clinical Immunology, October 10, 2014    Clinical Article

17 Management of hyperhidrosis Full Text Clinical, Cosmetic and Investigational Dermatology, November 18, 2014    Free full text    Clinical Article

18 Utility of sentinel node biopsy in patients with high-risk cutaneous squamous cell carcinoma European Journal of Surgical Oncology, November 14, 2014    Review Article

19 Invasive candidiasis and candidaemia in neonates and children: Update on current guidelines Mycoses, November 13, 2014    Review Article    Clinical Guideline

20 Evaluation of efficacy of cysteamine cream in the treatment of epidermal melasma: A randomized double blind placebo controlled study British Journal of Dermatology, October 6, 2014    Clinical Article

Indexed Journals in Dermatology: American Journal of Clinical Dermatology, Contact Dermatitis, Dermatologic Surgerymore