pHH3 Immunostaining Improves Interobserver Agreement of Mitotic Index in Thin Melanomas

The American Journal of Dermatopathology, 04/20/2012

Determination of mitotic rate (MR) with pHH3 immunostaining resulted in higher sensitivity in counting mitosis for all observers. Moreover, interobserver agreement was higher with pHH3. Immunostaining with pHH3 is a sensitive method to detect mitosis in thin cutaneous melanomas, with good reproducibility of MR between independent observers.

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