OnabotulinumtoxinA Dose-Ranging Study for Hyperdynamic Perioral Lines

Dermatologic Surgery, 06/14/2012

OnabotulinumtoxinA provides significant reductions in perioral lines (POLs) severity and high levels of subject satisfaction. Lack of dose response and fewer adverse events (AEs) suggest that treatment of hyperdynamic POLs with 7.5 U appears adequate for up to 16 weeks.

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