MC1R genotypes and risk of melanoma before age 40 years: A population-based case-control-family study

International Journal of Cancer, 05/02/2012

Melanocortin–1 receptor (MC1R) variants explained about 21% of the familial aggregation of melanoma. Some MC1R variants are important determinants of early–onset melanoma. The strength of association with melanoma differs according to the type and number of variants.

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