TNF-alpha increases lipogenesis via JNK and PI3K/Akt pathways in SZ95 human sebocytes

Journal of Dermatological Science, 03/22/2012

Tumor necrosis factor–alpha (TNF–alpha) induces lipogenesis in SZ95 human sebocytes through the JNK and phosphoinositide–3–kinase/Akt pathways. These results will be valuable in developing therapeutic strategies for control of seborrhea and acne.

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