Does autoreactivity play a role in atopic dermatitis

The Journal of Allergy and Clinical Immunology, 03/13/2012

The authors suggest that autoreactivity might be playing a causative role in atopic dermatitis (AD) based on the magnitude and specificity of the associations found; plausible mechanisms through IgE autoantibodies, IgG autoantibodies, and TH1 autoreactivity; and experimental elicitation of eczematous lesions after provocation.

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