Dermatology News & Articles

1 Risk factors for male lower urinary tract symptoms: the role of metabolic syndrome and androgenetic alopecia in a Latin American population Urology, May 7, 2013
Barbosa JABA et al. - This study aimed to evaluate the association of male lower urinary tract symptoms (LUTS) with metabolic syndrome (MetS) and androgenetic alopecia in a Latin American population. Components of the MetS were strongly associated with moderate and severe LUTS. WHR and cardiovascular events were independent predictors of voiding and storage symptoms, and MetS was an independent predictor of storage symptoms. alopecia was not an independent predictor of LUTS. ...

2 Association of Androgenetic Alopecia With Mortality From Diabetes Mellitus and Heart Disease Androgenetic Alopecia and Mortality JAMA Dermatology, May 16, 2013
Su LH et al. - Identifying predictors of mortality from diabetes mellitus (DM) and heart disease can help shape treatment strategies. Presence of androgenetic alopecia (AGA) might be such a predictor. AGA is an independent predictor of mortality from DM and heart disease in both sexes. This finding may have significant implications for the identification of risk factors for DM and heart disease in patients with moderate or severe AGA, regardless of whether MetS is present.

3 Inflammatory tinea capitis mimicking dissecting cellulitis in a postpubertal male: a case report and review of the literature Mycoses, April 30, 2013
Stein LL et al. - Tinea capitis in postpubertal patients is unusual and may be misdiagnosed as dissecting cellulitis. The authors report a case of a healthy 19-year-old Hispanic male presenting with a 2-month history of a large, painful subcutaneous boggy plaque on the scalp with patchy alopecia, erythematous papules, cysts and pustules. Although initially diagnosed as dissecting cellulitis, potassium hydroxide evaluation (KOH preparation) of the hair from the affected ...

4 Functional polymorphisms in cell death pathway genes FAS and FAS ligand and risk of alopecia areata Archives of Dermatological Research, May 2, 2013
Kalkan G et al. - FAS and FAS ligand (FASLG) are important proapoptotic proteins that have a significant function in regulating cell growth and apoptosis and play essential roles in many human autoimmune diseases. alopecia areata (AA) is hypothesized to be an organ-specific autoimmune disease mediated by T cells to the hair follicles. FASLG polymorphisms may have an effect on the risk of AA in the Turkish population. These findings provide an additional support to a genetic basis ...

5 T helper and regulatory T cell cytokines in the peripheral blood of active alopecia areata British Journal of Dermatology, May 7, 2013
Tembhre MK et al. - The aim of this investigation was to assess the role of hallmark cytokines of T-helper (Th1, Th2, and Th17) and regulatory T cells (Tregs) in the pathogenesis of AA and its clinical correlation. The increased levels of serum IL-2, IFN-γ, IL-13, IL-17A suggested altered T helper (Th1, Th2 and Th17) cell function and reduced serum TGF-β1 levels suggested defect in Tregs function. Therefore, enhanced T cell mediated immunity ...

6 Factors Influencing the Effectiveness of Scalp Cooling in the Prevention of Chemotherapy-Induced Alopecia The Oncologist, May 9, 2013
Komena MMC et al. - The success of scalp cooling in preventing or reducing chemotherapy-induced alopecia (CIA) is highly variable between patients and chemotherapy regimens. The outcome of hair preservation is often unpredictable and depends on various factors. The effectiveness of scalp cooling for hair preservation varies by chemotherapy type and dose, and probably by the degree and duration of cooling.

7 Association analysis of the HLA-C gene in Japanese alopecia areata Immunogenetics, April 30, 2013
Haida Y et al. - The aim of this study was to evaluate whether an allele of the HLA-C locus, HLA-C*07:04, which was strongly associated with AA in Chinese Hans, could be replicated in the Japanese population. The HLA-C locus was genotyped by the SSO method using 156 AA patients and 560 healthy controls. As a consequence, among the 17 alleles detected, only two alleles, C*04:01 (OR=2.25, CI 95 %=1.35–3.75, P=1.84E-03) and C*15:02 (OR=2.52, CI 95 %=1.37–4.64, ...

8 Patient Outcomes, Satisfaction, and Improvement in Headaches After Endoscopic Brow-lift JAMA Facial Plastic Surgery, May 10, 2013
Panella NJ et al. – To understand patient–reported outcomes, satisfaction, and recovery after EBL surgery to improve preoperative counseling. Endoscopic brow–lift is well tolerated and most patients are happy with the outcome. Relying on patient–reported information helps us to better understand the surgical experience and to improve preoperative counseling. Methods A retrospective telephone survey of 57 patients who had EBL or EBL with concurrent rhytidectomy to assess cosmetic and ...

9 Methods of hair loss evaluation. A comparison of TrichoScan with the modified wash test Experimental Dermatology, May 13, 2013
Guarrera M et al. - The reliability of the methods currently used for diagnosing hair loss is ill defined. The authors studied 41 subjects complaining of hair loss, including androgenetica alopecia and telogen effluvium, and compared the results obtained with the modified wash test (MWT) and TrichoScan. In conclusion, the clinical observation should be assisted by MWT and dermoscopy, leaving the biopsy for very difficult cases. TrichoScan is less useful and may be even misleading in TE.

10 Androgenetic alopecia (male pattern hair loss) in the United States: What treatments should primary care providers recommend? Journal of the American Academy of Nurse Practitioners, May 17, 2013
Chin EY - Androgenetic alopecia (AGA), or male pattern hair loss, affects up to 96% of Caucasian men. Characterized by gradual thinning and eventual loss of hair along frontotemporal, parietal, and vertex areas of the scalp, AGA is associated with low self-esteem, depression, and dissatisfaction with body appearance. Topical minoxidil 2%–5% 1 mL twice daily or finasteride 1 mg daily are recommended as first line treatments, followed by the use of Food and Drug ...