We have Ranked, Sorted and Summarized the Latest Clinical Articles.

1Assessment of serum levels of osteopontin, selenium and prolactin in patients with psoriasis compared with healthy controls, and their association with psoriasis severityClinical and Experimental Dermatology, May 27, 2015  Clinical Article
2Systematic review on the efficacy, safety, and cost-effectiveness of topical calcineurin inhibitors in atopic dermatitisDermatitis, May 27, 2015  Review Article
3Serum IL-33 levels are increased in patients with psoriasisClinical and Experimental Dermatology, May 27, 2015  Clinical Article
4Flexural eczema versus atopic dermatitisDermatitis, May 27, 2015  Review Article
5Body vectoring technique with Radiesse® for tightening of the abdomen, thighs, and brachial zoneClinical, Cosmetic and Investigational Dermatology, May 27, 2015  Full Text  Clinical Article
6Significance of dermatologic findings in a cohort of depleted uranium–exposed veterans of Iraqi conflictsDermatitis, May 27, 2015  Clinical Article
7Polysensitization and individual susceptibility to allergic contact dermatitisDermatitis, May 27, 2015  Clinical Article
8Dermoscopy of black skin: A cross-sectional study of clinical and dermoscopic features of melanocytic lesions in individuals with type V/VI skin compared to those with type I/II skinJournal of the American Academy of Dermatology, May 27, 2015  Clinical Article
9Vismodegib induces significant clinical response in locally advanced trichoblastic carcinomaBritish Journal of Dermatology, May 27, 2015  Clinical Article
10Drug resistance in Mycobacterium leprae from patients with leprosy in ChinaClinical and Experimental Dermatology, May 27, 2015  Clinical Article

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We have Ranked, Sorted and Summarized the Latest Clinical Articles.

1Using healthy skin to identify cancers originsWellcome Trust Sanger Institute News, May 27, 2015
2Cancer-associated DNA changes exist in a quarter of normal skin cellsUniversity of Cambridge News, May 22, 2015
3Surgery followed by ipilimumab treatment in melanoma patients improves survival, say Moffitt Cancer Center researchersH. Lee Moffitt Cancer Center & Research Institute News, May 21, 2015
4Revolutionary discovery could help tackle skin and heart conditionsThe University of Manchester News, May 18, 2015
5Wellcome support for synthetic skin that instructs body how to repair itselfThe University of Sydney News, May 14, 2015
6New cancer treatment and prevention studies signal major advances for children and adultsAmerican Society of Clinical Oncology (ASCO) News, May 14, 2015

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DCL1 is a tumor suppressor in melanoma patients

As reported in Modern Pathology, down-regulation of cytoplasmic and nuclear DLC1 is associated with poor overall survival and disease-specific 5-y survival in all melanoma patients. Combined down-regulation of cytoplasmic and nuclear DCL1 was associated with the worse survival for patients with metastatic melanoma.

Pantothenic acid effective for acne

As reported in Dermatology and Therapy, a pantothenic acid-based dietary supplement for 12 weeks reduced the total lesion count, number of inflammatory lesions, and DLQI in patients with mild-to-moderate acne (n=41) compared to placebo.

Infliximab effective in treatment of plaque-type psoriasis

As reported in the British Journal of Dermatology, of patients with plaque-type psoriasis (n=660) treated with infliximab (5 mg/kg) at weeks 0, 2, and 6, then q 8 weeks through week 50, 56.8% achieved PASI 75, 71.6% of whom maintained the response through week 98. Of patients who achieved PASI 75 by week 14, 64.7% maintained the response through week 50. Of patients who did not achieve PASI 75 by week 50, 66.3% achieved PASI 75 by week 98.

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Clinical Pearls

Clinical Pearl from Smartest DocSublingual immunotherapy appears to be efficacious for house dust mite-induced allergic rhinitis.

Clinical Pearl from Smartest DocRadiofrequency aesthetic treatments are optimal for patients wanting to avoid recovery time.

Clinical Pearl from Smartest DocIHC is sensitive and specific for BRAF V600E in melanoma.

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