Pharmacological management of pain during orthodontic treatment: a meta-analysis
Orthodontics & Craniofacial Research, 04/23/2012
Evidence Based Medicine
Angelopoulou MV et al. – Ibuprofen appears to lower orthodontic pain compared to placebo at 2 and 6 h after separators or archwire placement, but not at 24 h, when pain peaks.



