PPARγ delivered by Ch-GNPs onto titanium surfaces inhibits implant-induced inflammation and induces bone mineralization of MC-3T3E1 osteoblast-like cells
Clinical Oral Implants Research, 06/28/2012
Bhattarai G et al. – The novel gene delivery materials, like Ch–GNPs, can carry the PPARγ cDNA into the required areas of the implant surfaces, thus aiding to inhibit inflammation and promote osteoblast function. Thus, the PPARγ on implant surfaces may promote its clinical application on peri–implantitis or periodontitis like diseases.